THE BLOOD SUGAR PILL

1) “The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: a systematic review and meta-analysis.” Yin, R V et al. Nutrition & diabetes vol. 4,12 e145. 15 Dec. 2014, doi:10.1038/nutd.2014.42

2) “Bitter Melon (Momordica charantia L.) Fruit Bioactives Charantin and Vicine Potential for Diabetes Prophylaxis and Treatment.” Mahwish et al. Plants (Basel, Switzerland) vol. 10,4 730. 8 Apr. 2021, doi:10.3390/plants10040730

3) “mcIRBP-19 of Bitter Melon Peptide Effectively Regulates Diabetes Mellitus (DM) Patients' Blood Sugar Levels.” Hsu, Pang-Kuei et al. Nutrients vol. 12,5 1252. 28 Apr. 2020, doi:10.3390/nu12051252

4) “Efficacy of Aloe Vera Supplementation on Prediabetes and Early Non-Treated Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Zhang, Yiyi et al. Nutrients vol. 8,7 388. 23 Jun. 2016, doi:10.3390/nu8070388

5) “Identification of five phytosterols from Aloe vera gel as anti-diabetic compounds.” Tanaka, Miyuki et al. Biological & pharmaceutical bulletin vol. 29,7 (2006): 1418-22. doi:10.1248/bpb.29.1418

6) “Improvement of glucose and lipid profile status with Aloe vera in pre-diabetic subjects: a randomized controlled-trial.” Alinejad-Mofrad, Samaneh et al. Journal of diabetes and metabolic disorders vol. 14 22. 9 Apr. 2015, doi:10.1186/s40200-015-0137-2

7) “Evaluation of Antidiabetic and Antihyperlipidemic Effects of Hydroalcoholic Extract of Leaves of Ocimum tenuiflorum (Lamiaceae) and Prediction of Biological Activity of its Phytoconstituents.” Parasuraman, Subramani et al. Pharmacognosy research vol. 7,2 (2015): 156-65. doi:10.4103/0974-8490.151457

8) “Potential Dual Role of Eugenol in Inhibiting Advanced Glycation End Products in Diabetes: Proteomic and Mechanistic Insights.” Singh, Priyanka et al. Scientific reports vol. 6 18798. 7 Jan. 2016, doi:10.1038/srep18798

9) “Evaluation of hypoglycemic and antioxidant effect of Ocimum sanctum.” Sethi, Jyoti et al. Indian journal of clinical biochemistry : IJCB vol. 19,2 (2004): 152-5. doi:10.1007/BF02894276 

 

THE GUT PILL

1) Sinn DH, Song JH, Kim HJ, Lee JH, Son HJ, Chang DK, Kim YH, Kim JJ, Rhee JC, Rhee PL. Therapeutic effect of Lactobacillus acidophilus-SDC 2012, 2013 in patients with irritable bowel syndrome. Dig Dis Sci. 2008 Oct;53(10):2714-8. doi: 10.1007/s10620-007-0196-4. Epub 2008 Feb 15. PMID: 18274900.

2) Rerksuppaphol S, Rerksuppaphol L. A Randomized Double-blind Controlled Trial of Lactobacillus acidophilus Plus Bifidobacterium bifidum versus Placebo in Patients with Hypercholesterolemia. J Clin Diagn Res. 2015 Mar;9(3):KC01-4. doi: 10.7860/JCDR/2015/11867.5728. Epub 2015 Mar 1. PMID: 25954637; PMCID: PMC4413085.

3) Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics. 2009 Aug;124(2):e172-9. doi: 10.1542/peds.2008-2666. Epub 2009 Jul 27. PMID: 19651563.

4) Ouwehand AC, Nermes M, Collado MC, Rautonen N, Salminen S, Isolauri E. Specific probiotics alleviate allergic rhinitis during the birch pollen season. World J Gastroenterol. 2009 Jul 14;15(26):3261-8. doi: 10.3748/wjg.15.3261. PMID: 19598302; PMCID: PMC2710782.

5) Ishida Y, Nakamura F, Kanzato H, Sawada D, Yamamoto N, Kagata H, Oh-Ida M, Takeuchi H, Fujiwara S. Effect of milk fermented with Lactobacillus acidophilus strain L-92 on symptoms of Japanese cedar pollen allergy: a randomized placebo-controlled trial. Biosci Biotechnol Biochem. 2005 Sep;69(9):1652-60. doi: 10.1271/bbb.69.1652. PMID: 16195581.

6) IHilimire MR, DeVylder JE, Forestell CA. Fermented foods, neuroticism, and social anxiety: An interaction model. Psychiatry Res. 2015 Aug 15;228(2):203-8. doi: 10.1016/j.psychres.2015.04.023. Epub 2015 Apr 28. PMID: 25998000.

7) Arora D, Rani A, Sharma A. A review on phytochemistry and ethnopharmacological aspects of genus Calendula. Pharmacogn Rev. 2013 Jul;7(14):179-87. doi: 10.4103/0973-7847.120520. PMID: 24347926; PMCID: PMC3841996.

8) Bashir S, Janbaz KH, Jabeen Q, Gilani AH. Studies on spasmogenic and spasmolytic activities of Calendula officinalis flowers. Phytother Res. 2006 Oct;20(10):906-10. doi: 10.1002/ptr.1980. PMID: 16906636.

9) Bonaterra GA, Bronischewski K, Hunold P, Schwarzbach H, Heinrich EU, Fink C, Aziz-Kalbhenn H, Müller J, Kinscherf R. Anti-inflammatory and Anti-oxidative Effects of Phytohustil^® and Root Extract of Althaea officinalis L. on Macrophages in vitro. Front Pharmacol. 2020 Mar 17;11:290. doi: 10.3389/fphar.2020.00290. PMID: 32256361; PMCID: PMC7090173.

10) Sendker J, Böker I, Lengers I, Brandt S, Jose J, Stark T, Hofmann T, Fink C, Abdel-Aziz H, Hensel A. Phytochemical Characterization of Low Molecular Weight Constituents from Marshmallow Roots (Althaea officinalis) and Inhibiting Effects of the Aqueous Extract on Human Hyaluronidase-1. J Nat Prod. 2017 Feb 24;80(2):290-297. doi: 10.1021/acs.jnatprod.6b00670. Epub 2017 Jan 27. PMID: 28128955.

11) Peterson CT, Denniston K, Chopra D. Therapeutic Uses of Triphala in Ayurvedic Medicine. J Altern Complement Med. 2017 Aug;23(8):607-614. doi: 10.1089/acm.2017.0083. Epub 2017 Jul 11. PMID: 28696777; PMCID: PMC5567597.

 

THE BLOOD PRESSURE PILL

1) Asher GN, Viera AJ, Weaver MA, Dominik R, Caughey M, Hinderliter AL. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC Complement Altern Med. 2012 Mar 29;12:26. doi: 10.1186/1472-6882-12-26. PMID: 22458601; PMCID: PMC3350435.

2) Zhao CN, Meng X, Li Y, Li S, Liu Q, Tang GY, Li HB. Fruits for Prevention and Treatment of Cardiovascular Diseases. Nutrients. 2017 Jun 13;9(6):598. doi: 10.3390/nu9060598. PMID: 28608832; PMCID: PMC5490577.

3) Da-Costa-Rocha I, Bonnlaender B, Sievers H, Pischel I, Heinrich M. Hibiscus sabdariffa L. - a phytochemical and pharmacological review. Food Chem. 2014 Dec 15;165:424-43. doi: 10.1016/j.foodchem.2014.05.002. Epub 2014 May 27. PMID: 25038696.

4) Hopkins AL, Lamm MG, Funk JL, Ritenbaugh C. Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies. Fitoterapia. 2013 Mar;85:84-94. doi: 10.1016/j.fitote.2013.01.003. Epub 2013 Jan 17. PMID: 23333908; PMCID: PMC3593772.

5) Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, Beta T, Li HB. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). Foods. 2019 May 30;8(6):185. doi: 10.3390/foods8060185. PMID: 31151279; PMCID: PMC6616534.

6) Kulczyński B, Gramza-Michałowska A. The importance of selected spices in cardiovascular diseases. Postepy Hig Med Dosw (Online). 2016 Nov 14;70(0):1131-1141. doi: 10.5604/17322693.1224252. PMID: 27892897.

THE SERENITY PILL

1) Langade D, Kanchi S, Salve J, Debnath K, Ambegaokar D. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus. 2019 Sep 28;11(9):e5797. doi: 10.7759/cureus.5797. PMID: 31728244; PMCID: PMC6827862.

2) Pratte MA, Nanavati KB, Young V, Morley CP. An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera). J Altern Complement Med. 2014 Dec;20(12):901-8. doi: 10.1089/acm.2014.0177. PMID: 25405876; PMCID: PMC4270108.

3) Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019 Sep;98(37):e17186. doi: 10.1097/MD.0000000000017186. PMID: 31517876; PMCID: PMC6750292.

4) Abourashed EA, El-Alfy AT. Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.). Phytochem Rev. 2016 Dec;15(6):1035-1056. doi: 10.1007/s11101-016-9469-x. Epub 2016 May 10. PMID: 28082856; PMCID: PMC5222521.

5) Moinuddin G, Devi K, Kumar Khajuria D. Evaluation of the anti-depressant activity of Myristica fragrans (Nutmeg) in male rats. Avicenna J Phytomed. 2012 Spring;2(2):72-8. PMID: 25050233; PMCID: PMC4075663.

6) Dantas LP, de Oliveira-Ribeiro A, de Almeida-Souza LM, Groppo FC. Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction. Med Oral Patol Oral Cir Bucal. 2017 Jan 1;22(1):e95-e101. doi: 10.4317/medoral.21140. PMID: 27918731; PMCID: PMC5217504.

7) da Fonseca LR, Rodrigues RA, Ramos AS, da Cruz JD, Ferreira JLP, Silva JRA, Amaral ACF. Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential. ScientificWorldJournal. 2020 Jul 20;2020:6598434. doi: 10.1155/2020/6598434. PMID: 32765195; PMCID: PMC7387951.

8) Janda K, Wojtkowska K, Jakubczyk K, Antoniewicz J, Skonieczna-Żydecka K. Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review. Nutrients. 2020 Dec 19;12(12):3894. doi: 10.3390/nu12123894. PMID: 33352740; PMCID: PMC7766837.

 

THE BRAIN PILL

1) Lai PL, Naidu M, Sabaratnam V, Wong KH, David RP, Kuppusamy UR, Abdullah N, Malek SN. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54. doi: 10.1615/intjmedmushr.v15.i6.30. PMID: 24266378.

2) Ratto D, Corana F, Mannucci B, Priori EC, Cobelli F, Roda E, Ferrari B, Occhinegro A, Di Iorio C, De Luca F, Cesaroni V, Girometta C, Bottone MG, Savino E, Kawagishi H, Rossi P. Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging. Nutrients. 2019 Mar 27;11(4):715. doi: 10.3390/nu11040715. PMID: 30934760; PMCID: PMC6521003.

3) Brondino N, De Silvestri A, Re S, Lanati N, Thiemann P, Verna A, Emanuele E, Politi P. A Systematic Review and Meta-Analysis of Ginkgo biloba in Neuropsychiatric Disorders: From Ancient Tradition to Modern-Day Medicine. Evid Based Complement Alternat Med. 2013;2013:915691. doi: 10.1155/2013/915691. Epub 2013 May 28. PMID: 23781271; PMCID: PMC3679686.

4) Iriti M, Vitalini S, Fico G, Faoro F. Neuroprotective herbs and foods from different traditional medicines and diets. Molecules. 2010 May 14;15(5):3517-55. doi: 10.3390/molecules15053517. PMID: 20657497; PMCID: PMC6263339.

5) Lopresti AL. Salvia (Sage): A Review of its Potential Cognitive-Enhancing and Protective Effects. Drugs R D. 2017 Mar;17(1):53-64. doi: 10.1007/s40268-016-0157-5. PMID: 27888449; PMCID: PMC5318325.

 

THE IMMUNE PILL

1) Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw. 2001 Apr-Jun;12(2):290-6. PMID: 11399518.

2)Kinoshita E, Hayashi K, Katayama H, Hayashi T, Obata A. Anti-influenza virus effects of elderberry juice and its fractions. Biosci Biotechnol Biochem. 2012;76(9):1633-8. doi: 10.1271/bbb.120112. Epub 2012 Sep 7. PMID: 22972323.

3) Zielińska-Wasielica J, Olejnik A, Kowalska K, Olkowicz M, Dembczyński R. Elderberry (Sambucus nigra L.) Fruit Extract Alleviates Oxidative Stress, Insulin Resistance, and Inflammation in Hypertrophied 3T3-L1 Adipocytes and Activated RAW 264.7 Macrophages. Foods. 2019 Aug 8;8(8):326. doi: 10.3390/foods8080326. PMID: 31398785; PMCID: PMC6724042.

4) Hudson JB. Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases. J Biomed Biotechnol. 2012;2012:769896. doi: 10.1155/2012/769896. Epub 2011 Oct 26. PMID: 22131823; PMCID: PMC3205674.

5) Zhai Z, Liu Y, Wu L, Senchina DS, Wurtele ES, Murphy PA, Kohut ML, Cunnick JE. Enhancement of innate and adaptive immune functions by multiple Echinacea species. J Med Food. 2007 Sep;10(3):423-34. doi: 10.1089/jmf.2006.257. PMID: 17887935; PMCID: PMC2362099.

6) Huang R, Zhao M, Yang X, Huang J, Yang Y, Chen B, Tan J, Huang J, Li Z, Lv Y, Ji G. Effects of Prunella vulgaris on the mice immune function. PLoS One. 2013 Oct 30;8(10):e77355. doi: 10.1371/journal.pone.0077355. PMID: 24204816; PMCID: PMC3813705.

7) Das G, Shin HS, Leyva-Gómez G, Prado-Audelo MLD, Cortes H, Singh YD, Panda MK, Mishra AP, Nigam M, Saklani S, Chaturi PK, Martorell M, Cruz-Martins N, Sharma V, Garg N, Sharma R, Patra JK. Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials. Front Pharmacol. 2021 Feb 8;11:602364. doi: 10.3389/fphar.2020.602364. PMID: 33628175; PMCID: PMC7898063.

8) Jung SJ, Jung ES, Choi EK, Sin HS, Ha KC, Chae SW. Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): a randomized and double-blind clinical trial. BMC Complement Altern Med. 2019 Mar 29;19(1):77. doi: 10.1186/s12906-019-2483-y. PMID: 30925876; PMCID: PMC6441223.

 

THE LIVER PILL

1) Gao Q, Yang M, Zuo Z. Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L. Acta Pharmacol Sin. 2018 May;39(5):787-801. doi: 10.1038/aps.2018.32. Epub 2018 Apr 26. PMID: 29698388; PMCID: PMC5943914.

2) Alhusaini A, Fadda L, Hasan IH, Ali HM, El Orabi NF, Badr AM, Zakaria E, Alenazi AM, Mahmoud AM. Arctium lappa Root Extract Prevents Lead-Induced Liver Injury by Attenuating Oxidative Stress and Inflammation, and Activating Akt/GSK-3β Signaling. Antioxidants (Basel). 2019 Nov 24;8(12):582. doi: 10.3390/antiox8120582. PMID: 31771282; PMCID: PMC6943639.

3) He Y, Fan Q, Cai T, Huang W, Xie X, Wen Y, Shi Z. Molecular mechanisms of the action of Arctigenin in cancer. Biomed Pharmacother. 2018 Dec;108:403-407. doi: 10.1016/j.biopha.2018.08.158. Epub 2018 Sep 17. PMID: 30236849.

4) Bijak M. Silybin, a Major Bioactive Component of Milk Thistle (Silybum marianum L. Gaernt.)-Chemistry, Bioavailability, and Metabolism. Molecules. 2017 Nov 10;22(11):1942. doi: 10.3390/molecules22111942. PMID: 29125572; PMCID: PMC6150307.

5) Federico A, Dallio M, Loguercio C. Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. Molecules. 2017 Jan 24;22(2):191. doi: 10.3390/molecules22020191. PMID: 28125040; PMCID: PMC6155865.

6) Goyal A, Sharma V, Upadhyay N, Gill S, Sihag M. Flax and flaxseed oil: an ancient medicine & modern functional food. J Food Sci Technol. 2014 Sep;51(9):1633-53. doi: 10.1007/s13197-013-1247-9. Epub 2014 Jan 10. PMID: 25190822; PMCID: PMC4152533.

7) Zhang X, Wang H, Yin P, Fan H, Sun L, Liu Y. Flaxseed oil ameliorates alcoholic liver disease via anti-inflammation and modulating gut microbiota in mice. Lipids Health Dis. 2017 Feb 22;16(1):44. doi: 10.1186/s12944-017-0431-8. PMID: 28228158; PMCID: PMC5322643.

 

THE URIC ACID PILL

1) Chen PE, Liu CY, Chien WH, Chien CW, Tung TH. Effectiveness of Cherries in Reducing Uric Acid and Gout: A Systematic Review. Evid Based Complement Alternat Med. 2019 Dec 4;2019:9896757. doi: 10.1155/2019/9896757. PMID: 31885677; PMCID: PMC6914931.

2) Levers K, Dalton R, Galvan E, O'Connor A, Goodenough C, Simbo S, Mertens-Talcott SU, Rasmussen C, Greenwood M, Riechman S, Crouse S, Kreider RB. Effects of powdered Montmorency tart cherry supplementation on acute endurance exercise performance in aerobically trained individuals. J Int Soc Sports Nutr. 2016 May 26;13:22. doi: 10.1186/s12970-016-0133-z. PMID: 27231439; PMCID: PMC4880859.

3) RSchumacher HR, Pullman-Mooar S, Gupta SR, Dinnella JE, Kim R, McHugh MP. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage. 2013 Aug;21(8):1035-41. doi: 10.1016/j.joca.2013.05.009. Epub 2013 May 31. PMID: 23727631.

4) Howatson G, Bell PG, Tallent J, Middleton B, McHugh MP, Ellis J. Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. Eur J Nutr. 2012 Dec;51(8):909-16. doi: 10.1007/s00394-011-0263-7. Epub 2011 Oct 30. PMID: 22038497.

5) Cheng X, Wang H, Yang J, Cheng Y, Wang D, Yang F, Li Y, Zhou D, Wang Y, Xue Z, Zhang L, Zhang Q, Yang L, Zhang R, Da Y. Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice. Biomed Pharmacother. 2018 Jun;102:464-471. doi: 10.1016/j.biopha.2018.03.060. Epub 2018 Apr 5. PMID: 29579707.

6) Afzali A, Weiss NS, Boyko EJ, Ioannou GN. Association between serum uric acid level and chronic liver disease in the United States. Hepatology. 2010 Aug;52(2):578-89. doi: 10.1002/hep.23717. PMID: 20683957.

7) Predes FS, Ruiz AL, Carvalho JE, Foglio MA, Dolder H. Antioxidative and in vitro antiproliferative activity of Arctium lappa root extracts. BMC Complement Altern Med. 2011 Mar 23;11:25. doi: 10.1186/1472-6882-11-25. PMID: 21429215; PMCID: PMC3073957.

8) Gao Q, Yang M, Zuo Z. Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L. Acta Pharmacol Sin. 2018 May;39(5):787-801. doi: 10.1038/aps.2018.32. Epub 2018 Apr 26. PMID: 29698388; PMCID: PMC5943914.

9) Al-Asmari AK, Athar MT, Kadasah SG. An Updated Phytopharmacological Review on Medicinal Plant of Arab Region: Apium graveolens Linn. Pharmacogn Rev. 2017 Jan-Jun;11(21):13-18. doi: 10.4103/phrev.phrev_35_16. PMID: 28503047; PMCID: PMC5414449.

10) Stiani SN, Syahidah FM, Fikriani H, Subarnas A, Rusdiana T. Anticalculi Activity of Apigenin and Celery (Apium graveolens L.) Extract in Rats Induced by Ethylene Glycol-Ammonium Chloride. J Pharm Bioallied Sci. 2019 Dec;11(Suppl 4):S556-S561. doi: 10.4103/jpbs.JPBS_202_19. Epub 2019 Dec 30. PMID: 32148363; PMCID: PMC7020841.

 

THE LIBIDO PILL

1) Fursenco C, Calalb T, Uncu L, Dinu M, Ancuceanu R. Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities. Biomolecules. 2020 Nov 30;10(12):1619. doi: 10.3390/biom10121619. PMID: 33266185; PMCID: PMC7761148.

2) Dording CM, Schettler PJ, Dalton ED, Parkin SR, Walker RS, Fehling KB, Fava M, Mischoulon D. A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evid Based Complement Alternat Med. 2015;2015:949036. doi: 10.1155/2015/949036. Epub 2015 Apr 14. PMID: 25954318; PMCID: PMC4411442.

3) Concerto C, Rodolico A, Meo V, Chiappetta D, Bonelli M, Mineo L, Saitta G, Stuto S, Signorelli MS, Petralia A, Lanza G, Aguglia E. A Systematic Review on the Effect of Nutraceuticals on Antidepressant-Induced Sexual Dysfunctions: From Basic Principles to Clinical Applications. Curr Issues Mol Biol. 2022 Jul 25;44(8):3335-3350. doi: 10.3390/cimb44080230. PMID: 35892716; PMCID: PMC9332380.

4) Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, Mischoulon D. A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction. CNS Neurosci Ther. 2008 Fall;14(3):182-91. doi: 10.1111/j.1755-5949.2008.00052.x. PMID: 18801111; PMCID: PMC6494062.

5) JianFeng C, PengYing Z, ChengWei X, TaoTao H, YunGui B, KaoShan C. Effect of aqueous extract of Arctium lappa L. (burdock) roots on the sexual behavior of male rats. BMC Complement Altern Med. 2012 Feb 1;12:8. doi: 10.1186/1472-6882-12-8. PMID: 22296876; PMCID: PMC3299611.

6) Chauhan NS, Sharma V, Dixit VK, Thakur M. A review on plants used for improvement of sexual performance and virility. Biomed Res Int. 2014;2014:868062. doi: 10.1155/2014/868062. Epub 2014 Aug 18. PMID: 25215296; PMCID: PMC4151601.

 

THE STONE BREAKER PILL

1) Lee NY, Khoo WK, Adnan MA, Mahalingam TP, Fernandez AR, Jeevaratnam K. The pharmacological potential of Phyllanthus niruri. J Pharm Pharmacol. 2016 Aug;68(8):953-69. doi: 10.1111/jphp.12565. Epub 2016 Jun 10. PMID: 27283048.

2) Nisar MF, He J, Ahmed A, Yang Y, Li M, Wan C. Chemical Components and Biological Activities of the Genus Phyllanthus: A Review of the Recent Literature. Molecules. 2018 Oct 8;23(10):2567. doi: 10.3390/molecules23102567. PMID: 30297661; PMCID: PMC6222918.

3) Al-Asmari AK, Athar MT, Kadasah SG. An Updated Phytopharmacological Review on Medicinal Plant of Arab Region: Apium graveolens Linn. Pharmacogn Rev. 2017 Jan-Jun;11(21):13-18. doi: 10.4103/phrev.phrev_35_16. PMID: 28503047; PMCID: PMC5414449.

4) Stiani SN, Syahidah FM, Fikriani H, Subarnas A, Rusdiana T. Anticalculi Activity of Apigenin and Celery (Apium graveolens L.) Extract in Rats Induced by Ethylene Glycol-Ammonium Chloride. J Pharm Bioallied Sci. 2019 Dec;11(Suppl 4):S556-S561. doi: 10.4103/jpbs.JPBS_202_19. Epub 2019 Dec 30. PMID: 32148363; PMCID: PMC7020841.

5) Shankar E, Goel A, Gupta K, Gupta S. Plant flavone apigenin: An emerging anticancer agent. Curr Pharmacol Rep. 2017 Dec;3(6):423-446. doi: 10.1007/s40495-017-0113-2. Epub 2017 Oct 14. PMID: 29399439; PMCID: PMC5791748. 

6) Kwon Y. Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia. Food Sci Biotechnol. 2019 Apr 17;28(6):1599-1606. doi: 10.1007/s10068-019-00605-9. PMID: 31807332; PMCID: PMC6859144. 

7) Chittur S, Parr B, Marcovici G. Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract. Evid Based Complement Alternat Med. 2011;2011:985345. doi: 10.1093/ecam/nep102. Epub 2011 Jun 8. PMID: 19692448; PMCID: PMC3137880. 

8) Chittur S, Parr B, Marcovici G. Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract. Evid Based Complement Alternat Med. 2011;2011:985345. doi: 10.1093/ecam/nep102. Epub 2011 Jun 8. PMID: 19692448; PMCID: PMC3137880.

 

THE JOINT PAIN PILL

1) Fadus MC, Lau C, Bikhchandani J, Lynch HT. Curcumin: An age-old anti-inflammatory and anti-neoplastic agent.” J Tradit Complement Med. 2016 Sep 9;7(3):339-346. doi: 10.1016/j.jtcme.2016.08.002. PMID: 28725630; PMCID: PMC5506636.

2) Askari G, Sahebkar A, Soleimani D, Mahdavi A, Rafiee S, Majeed M, Khorvash F, Iraj B, Elyasi M, Rouhani MH, Bagherniya M. “The efficacy of curcumin-piperine co-supplementation on clinical symptoms, duration, severity, and inflammatory factors in COVID-19 outpatients: a randomized double-blind, placebo-controlled trial.” Trials. 2022 Jun 6;23(1):472. doi: 10.1186/s13063-022-06375-w. PMID: 35668500; PMCID: PMC9167899.

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